Antidiabetic Activity of Extracts of Terminalia brownii Fresen. Stem Bark in Mice
| dc.coverage | Health Facility | |
| dc.creator | Niguse Meles Alemaa | |
| dc.creator | Gebretsadkan Hintsa Teklu | |
| dc.creator | Chirle de Oliveira Raphaelli | |
| dc.creator | Elisa dos Santos Pereira | |
| dc.creator | Taiane Mota Camargo | |
| dc.creator | Marcia Vizzotto | |
| dc.creator | Ephrem Mebrahtu Araya | |
| dc.creator | Desalegn Getnet Demsie | |
| dc.creator | Hagazi Gebremedhin Kassaye | |
| dc.creator | Haylay Araya | |
| dc.creator | Aman Karim | |
| dc.date.accessioned | 2025-03-22T07:43:58Z | |
| dc.description.abstract | The dataset from the study on Terminalia brownii evaluates its antidiabetic properties through various experiments. It includes the extraction of the stem bark using 80% methanol, acute toxicity assessments in female Swiss albino mice, and in vitro ?-amylase inhibition tests. In vivo experiments were conducted by inducing diabetes in mice with streptozotocin (STZ) and measuring blood glucose levels and glucose tolerance after administration of the crude extract and its solvent fractions. Additionally, preliminary phytochemical screening identified the presence of bioactive compounds. Statistical analysis was performed to assess the significance of the results, providing insights into the potential therapeutic effects of T. brownii on diabetes management. | |
| dc.format | SPSS: .sav | |
| dc.identifier.doi | 10.83385/trdmc-3efd | |
| dc.identifier.uri | https://rdmcrepo.thri.gov.et/handle/123456789/19 | |
| dc.identifier.uri | https://api.datacite.org/10.82208/trdmc-253 | |
| dc.identifier.uri | https://api.datacite.org/10.82208/trdmc-253 | |
| dc.identifier.uri | https://api.datacite.org/10.82208/trdmc-253 | |
| dc.language | English | |
| dc.publisher | TRDMC | |
| dc.rights | CC BY 4.0 | |
| dc.subject | Diabetes mellitus; streptozotocin; amylase; medicinal plant | |
| dc.title | Antidiabetic Activity of Extracts of Terminalia brownii Fresen. Stem Bark in Mice | |
| dc.type | Dataset | |
| trdmc.cleanedFormat | SPSS: .sav | |
| trdmc.coverageSex | Male and Female Mice | |
| trdmc.dataAccess | Accessible upon reasonable request | |
| trdmc.dataCategory | other clinical trail | |
| trdmc.dataGeneratingUnit | College of Medicine and Health Sciences | |
| trdmc.dataQualityStatus | Verified | |
| trdmc.dateDataCollectionStarted | 1905-07-09 | |
| trdmc.inclusionExclusionCriteria | Mothers who lived in the woredas (District) for at least 6 months were included mothers who were critically ill or unable to respond were excluded from the study | |
| trdmc.isReportDataAvailable | yes | |
| trdmc.organizationGeneratingData | Adigrat University | |
| trdmc.publicationStatus | Published | |
| trdmc.publicationurl | http://www.dovepress.com/testimonials.php to read real quotes from published authors. | |
| trdmc.rawCleanDataAvailable | Yes | |
| trdmc.sampleSize | 36 mice | |
| trdmc.samplingMethod | Systematic random sampling | |
| trdmc.studyDesign | Lab | |
| trdmc.studyPopulation | Experimental study, case and control | |
| trdmc.subject | Health and health related data |